TGFA anticorps
Aperçu rapide pour TGFA anticorps (ABIN5676024)
Antigène
Voir toutes TGFA AnticorpsReactivité
Hôte
Clonalité
Conjugué
Application
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Réactivité croisée (Details)
- human TGFalpha 100%. (Neutralizing antibody)We found no crossreactivty to other cytokines such as hTGFß, hEGF, hPDGf, hTNF. hEPO, hIGF, 1mg per ml. hIL-1, hIL-2, hIL-3, hIL-4, hIL-5, hIL-6, hIL-7, hIL-8, hIL-9, hIL-10, hIL-11,and hIL-12
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Purification
- Purified
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niveau d'endotoxine
- <0.1 EU per 1 µg of the antibody as determined by the LAL method.
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Immunogène
- TGF alpha antibody was raised in goat using E. coli-derived recombinant human TGF-alpha as the immunogen.
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Isotype
- IgG
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Indications d'application
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ELISA: 2-8 µg/mL, IHC: 15 µg/mL, WB: 1 µg/mL
Optimal conditions should be determined by the investigator. -
Restrictions
- For Research Use only
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Format
- Lyophilized
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Reconstitution
- Reconstitute with PBS buffer.
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Concentration
- Lot specific
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Buffer
- Supplied as a lyophilized powder.
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Conseil sur la manipulation
- Avoid repeated freeze/thaw cycles.
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Stock
- 4 °C/-20 °C
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Stockage commentaire
- Store at -20 °C until reconstitution. Following reconstitution product may be stored at 4 °C in the short term. For long term storage aliquot and freeze at -20 °C.
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- TGFA (Transforming Growth Factor, alpha (TGFA))
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Autre désignation
- TGF alpha
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Sujet
- Transforming growth factor alpha (TGF- alpha) is upregulated in some human cancers. It is produced in macrophages, brain cells, and keratinocytes, and induces epithelial development. It is closely related to EGF, and can also bind to the EGF receptor with similar effects . TGF alpha stimulates neural cell proliferation in the adult injured brain.
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Pathways
- Signalisation NF-kappaB, Signalisation RTK, EGFR Signaling Pathway
Antigène
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